"Editor J. William Schopf has assembled a council of shamans to tell the scientific versions of the story
of the origins of life....Many of them have led, and all have been honored by, the International Society for the
Study of the Origin of Life; all have made monumental contributions to the field."
--American Scientist
Publisher Web Site, June, 2004
Summary
Always a controversial and compelling topic, the origin of life on Earth was considered taboo as an area of
inquiry for science as recently as the 1950s. Since then, however, scientists working in this area have made remarkable
progress, and an overall picture of how life emerged is coming more clearly into focus. We now know, for example,
that the story of life's origin begins not on Earth, but in the interiors of distant stars. This book brings a
summary of current research and ideas on life's origin to a wide audience. The contributors, all of whom received
the Oparin/Urey Gold Medal of the International Society for the Study of the Origin of Life, are luminaries in
the fields of chemistry, paleobiology, and astrobiology, and in these chapters they discuss their life's work:
understanding the what, when, and how of the early evolution of life on Earth. Presented in nontechnical language
and including a useful glossary of scientific terms, Life's Origin gives a state-of-the-art encapsulation of the
fascinating work now being done by scientists as they begin to characterize life as a natural outcome of the evolution
of cosmic matter.
Table of Contents
List of Figures and Tables
Introduction: The What, When, and How of Life's Beginnings
1. Historical Understanding of Life's Beginnings
John Oro
What Is Life?
Beliefs and Hypotheses on the Origin of Life
Chemical Evolution
Personal Reminiscences
Cosmological Evolution and the Origin of Life
The Earth-Moon System
Exploration of the Solar System
Life Beyond the Solar System
Epilogue
References
2. From Big Bang to Primordial Planet: Setting the Stage for the Origin of Life
Alan W. Schwartz and Sherwood Chang
Introduction
Origin of the Biogenic Elements
Origin of the Solar System
Earth
Further Reading
3. Formation of the Building Blocks of Life
Stanley L. Miller and Antonio Lazcano
Introduction
The Heterotrophic Origin of Life
Prebiotic Syntheses of Amino Acids
Synthesis of Nucleic Acid Bases
Prebiotic Synthesis of Sugars
Hydrothermal Vents and the Origin of Life
Extraterrestrial Organic Compounds and Prebiotic Evolution
An Autotrophic Origin of Life?
Have Too Many Cooks Spoiled the Soup?
References
4. From Building Blocks to the Polymers of Life
James P. Ferris
The Biopolymers in the First Life
The RNA World: The Prebiotic Synthesis of RNA
The Role of Polypeptides in the Origin of Life
Conclusions
References
Further Reading
5. The Origin of Biological Information
Leslie E. Orgel
Introduction
The RNA World
What's Wrong with the Molecular Biologist's Dream?
The Metabolist Argument
Conclusion and Outlook
References
6. When Did Life Begin?
J. William Schopf
Introduction
Evidence from Living Organisms
Evidence from the Rock Record
When Was Earth Ready for Life?
The What and When of Life's Beginnings
Further Reading
