This comprehensive, unified text on the principles and practice of clinical trials presents a detailed account
of how to conduct the trials. It describes the design, analysis, and interpretation of clinical trials in a non-technical
manner and provides a general perspective on their historical development, current status, and future strategy.
Features examples derived from the author's personal experience.
Table of Contents
Introduction: The Rationale of Clinical Trials.
The Historical Development of Clinical Trials.
Organization and Planning.
The Justification for Randomized Controlled Trials.