Macomber, Roger S. : University of Cincinnati Main Campus
Roger S. Macomber was Professor of Chemistry at the University of Cincinnati, Ohio, from 1969-1997, and is currently
Professor of Chemistry at Pepperdine University. He is the author of nearly 100 scientific and professional articles,
as well as several monographs, including The Vocabulary of Organic Chemistry, NMR Spectroscopy: Essential Theory
and Practice, and Organic Chemistry, Volumes I and II.
Summary
Nuclear magnetic resonance (NMR) spectroscopy is the study of molecular structure. It is a growing technique
particularly in biochemistry and medicinal chemistry, that provides detailed information on molecular structure
and dynamics that other methods cannot. Assuming only a first-year chemistry course for background, this practical
guide describes all the necessary details of NMR spectral analysis.
Table of Contents
Spectroscopy: Some Preliminary Considerations.
Magnetic Properties of Nuclei.
Obtaining an NMR Spectrum.
Correlating Proton Chemical Shifts with Molecular Structure.
First-Order (Weak) Spin-Spin Coupling.
Factors that Influence the Sign and Magnitude of J: Second-Order (Strong) Coupling Effects.
The Study of Dynamic Processes by NMR.
Electron Paramagnetic Resonance Spectroscopy and Chemically Induced Dynamic Nuclear Polarization.
Two-Dimensional Nuclear Magnetic Resonance.
NMR Studies of Biologically Important Molecules.