Now in its second edition, Drugs and Human Lactation is a comprehensive guide to the content and consequences
of xenobiotics and micronutrients in human milk, and remains by far the most thorough and extensive work available
on this subject. The excellent methodology used for the compilation of the 1st edition has been retained.
It begins with an outline of the processes by which substances enter milk during its formation, the effects of
drugs on the milk production process, the main determinants of drug excretion into milk and their disposition in
the child. There follows an analysis of current data on 234 individual drugs, describing the extent of their passage
into human milk, and assessing the risk to the suckling infant. Vitamins and essential trace elements, and radiopharmaceuticals
are similarly reviewed. Also included is an account of the factors that influence the passage of environmental
and occupational chemicals into milk. The result is a complete overview of what is known and proven, with clear
pointers to matters which require further study, and brings the various subject areas up to date. Risks, uncertainties
and false alarms which exist have been defined in such a way that they can be avoided.
Once again, Drugs and Human Lactation provides a comprehensive guide to the content and consequences of substances
in milk. The volume will provide a rational basis for making therapeutic decisions in women who seek to breast-feed.