Author of more than a dozen research articles, Stan Reents, PharmD, is editor in chief of Clinical Pharmacology,
an internationally acclaimed electronic drug reference for health care professionals.
Dr. Reents has been a certified personal trainer and has 14 years of experience as clinical pharmacist at hospitals
in Illinois, Florida, and Missouri. He has taught pharmacology at the University of Florida, Purdue University,
and the University of Illinois. He earned his PharmD from the University of the Pacific.
Dr. Reents lives in Tampa, Florida. He is an avid tennis player.
Summary
While drug and supplement use has increased substantially in recent years, there is a lack of firm understanding
about how these substances can affect health and exercise. With Sport and Exercise Pharmacology, physicians and
sports medicine specialists will learn how various commonly used drugs and supplements can affect exercise performance
in their patients and athletes. Practical guidelines are offered so that professionals can closely monitor and
circumvent adverse reactions to drug therapies.
But what are the effects of exercise on the drug itself? This issue is also explored in this valuable reference
that covers a wide range of substances including supplements and over-the-counter, prescription, and social drugs,
and highlights both sports medicine and clinical medicine issues. The role of exercise in actually preventing the
need for drugs is a key message of the reference and a central reason that author Stan Reents, PharmD, has created
the book.
With this essential resource, you will learn how drugs affect physical activities and how exercise can change the
effects of drugs. Among the issues explored in Sport and Exercise Pharmacology are the following:
How can drug therapy treat and prevent exercise-induced bronchospasm?
What is the impact of athletes� use of analgesics?
Lovastatin is known to be associated with muscle injury�does this necessarily mean that a person taking this
lipid-lowering drug should not lift weights?
Physicians often prescribe aerobic exercise to help lower blood pressure, but they also may prescribe diuretics�should
a person taking a diuretic always avoid playing tennis on a hot day?
Under what circumstances may creatine, androstenedione, and DHEA supplementation actually help performance,
and when is it a waste of money?
For what kinds of exercise does caffeine appear to boost performance? Are there any sporting events for which
alcohol appears not to have a deleterious effect?
How can exercise reduce the need for drug therapy for many chronic medical conditions?
The book covers cardiopulmonary agents, hormonal agents (including growth hormone, anabolic steroids, and erythropoietin),
metabolic agents (including creatine, NSAIDS, and nutritional supplements), and socially used drugs. The text concludes
with an examination of how exercise can be used as a preventive measure in reducing a patient�s need for drug therapy.
Case studies at the beginning of each chapter provide real-world examples of the interactions between drugs and
exercise. A closing bibliography summarizes dozens of resources on drugs and exercise.
This practical reference is your best resource to better understanding the varied and dynamic interactions between
exercise and pharmacology, including the pivotal role that regular exercise plays in reducing the need for some
drug therapies. This book will prove invaluable to any health professional whose clients exercise or engage in
sports, and to any trainer, therapist, or fitness expert whose clients use supplements, banned substances, or prescription
or over-the-counter drugs.
Table of Contents
Credits
Acknowledgments
Introduction
Better Clinical Research is Needed
References
Part I: Cardiopulmonary Agents Chapter 1. Beta-Receptor Antagonists (Beta-Blockers)
How Exercise Affects the Action of Beta-Blockers
How Beta-Blockers Affect Exercisers
How Beta-Blockers Affect Exercise Performance
Avoiding Potential Complications
References
Chapter 2. Diuretics
How Exercise Affects the Action of Diuretics
How Diuretics Affect Exercisers
How Diuretics Affect Exercise Performance
Avoiding Potential Complications
References
Chapter 3. Other Antihypertensive Agents
How Exercise Affects the Action of Antihypertensive Drugs
How Antihypertensive Drugs Affect Exercisers
How Antihypertensive Drugs Affect Exercise Performance
Can a Conditioning Effect Be Achieved While Taking Antihypertensive Drugs?
Avoiding Potential Complications
References
Chapter 4. Sympathomimetics
How Exercise Affects the Action of Sympathomimetics
How Sympathomimetics Affect Exercisers
How Sympathomimetics Affect Exercise Performance
Avoiding Potential Complications
References
Chapter 5. Bronchodilators and Respiratory Anti-Inflammatory Agents
Exercise-Induced Bronchoconstriction
Introduction to Respiratory Drugs
How Exercise Affects the Action of Bronchodilators and Respiratory Anti-Inflammatory Agents
How Respiratory Agents Affect Exercisers
How Respiratory Agents Affect Exercise Performance
Avoiding Potential Complications
References
Part II: Hormonal Agents
Chapter 6. Human Growth Hormone
Somatrem and Somatropin
How Exercise Affects the Action of Growth Hormone
How Growth Hormone Affects Exercisers
How Growth Hormone Affects Exercise Performance
Avoiding Potential Complications
References
Chapter 7. Androgenic-Anabolic Steroids
How Exercise Affects the Action of Androgenic-Anabolic Steroids
How Androgenic-Anabolic Steroids Affect Exercisers
How Androgenic-Anabolic Steroids Affect Exercise Performance
Avoiding Potential Complications
References
Part III: Metabolic Agents Chapter 8. Creatine
How Exercise Affects the Action of Creatine Supplements
Dosing Strategies and Effects on Tissue Concentrations of Creatine
How Creatine Supplements Affect Exercisers
How Creatine Supplements Affect Exercise Performance
Dietary Factors and Their Effects on the Response to Creatine
Avoiding Potential Complications
References
Chapter 9. Iron and Erythropoietin (Epoetin Alfa)
Hematinic Agents
How Exercise Affects the Action of Epoetin Alfa and Iron
How Epoetin Alfa and Iron Supplements Affect Exercisers
How Epoetin Alfa and Iron Supplements Affect Exercise Performance
Avoiding Potential Complications
References
Chapter 10. Antilipemic Agents
Antilipemic Drugs
How Exercise Affects the Action of Antilipemic Agents
How Antilipemic Agents Affect Exercisers
How Antilipemic Agents Affect Exercise Performance
Avoiding Potential Complications
References
Chapter 11. Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) and Salicylates
Anti-Inflammatory Agents
How Exercise Affects the Action of Anti-Inflammatory Agents
How Anti-Inflammatory Agents Affect Exercisers
How Anti-Inflammatory Agents Affect Exercise Performance
Avoiding Potential Complications
References
Chapter 12. Nutritional Supplements
Pharmaceutical or Nutraceutical? The DSHEA Law of 1994
DHEA and Androstenedione
Chromium
Coenzyme Q-10
Sodium Bicarbonate
References
Part IV: Socially Used Drugs Chapter 13. Caffeine
How Exercise Affects the Action of Caffeine
How Caffeine Affects Exercisers
How Caffeine Affects Exercise Performance
Avoiding Potential Complications
References
Chapter 14. Ethanol
How Exercise Affects the Action of Ethanol
How Ethanol Affects Exercisers
How Ethanol Affects Exercise Performance
Avoiding Potential Complications
References
Chapter 15. Amphetamines and Cocaine
How Exercise Affects the Action of Cocaine and Amphetamines
How Cocaine and Amphetamines Affect Exercisers
How Amphetamines and Cocaine Affect Exercise Performance
Avoiding Potential Complications
References
Part V: Final Thoughts Chapter 16. Exercise: The Overlooked Prescription
Improving the Therapeutic Use of Exercise
Becoming More Proactive in Recommending Exercise
Guidelines for Physicians, Trainers, Teachers, and Parents
References
Additional Information Sources for Drugs and Exercise
About the Author
