Completely updated, the 4th edition of this classic resource offers the current, comprehensive coverage of immunology you need to stay on the cutting-edge of clinical laboratory science. It provides a solid foundation of knowledge and skills to take you from basic immunologic mechanisms and serologic concepts to the theory behind the procedures youll perform in the lab, including automated techniques. It also explores the medical applications of clinical laboratory science, with information on disorders of infectious and immunologic origin, as well as topics such as transplantation and tumor immunology. Learning objectives, review questions, step-by-step procedures, and case studies help you master key concepts and prepare you to succeed in todays modern laboratory environment. Author Mary Louise Turgeon, a leader in the field of clinical laboratory science, shares with you her wealth of knowledge and experience in this outstanding textbook. The books two-color design provides you with at-a-glance access to special features and vital information. In-depth chapter outlines prepare you for the material you will be learning in each chapter and help you see how the topics flow and connect to each other. Learning objectives at the beginning of each chapter allow you to set study goals and assess your progress as you move through the textbook. Highlights at the end of every chapter summarize the most important points you should take away from the chapter. Review questions help you assess and reinforce your understanding of chapter content. Case studies in many of the chapters allow you to see how key concepts apply to real-life scenarios. Hands-on procedure coverage in many chapters offer detailed descriptions of exactly what happens during every step of laboratory procedures. A convenient glossary of key terms in the back of the book provides quick access to definitions for new or unfamiliar words. In addition to completely updated content throughout, four new chapters on quality assurance and quality control, basic serologic laboratory techniques, point-of-care testing, and vaccines bring you the latest advances in the field. Expanded coverage of automated procedures and molecular techniques keep you up to date on technology and research. A new full-color insert serves as a vivid visual reference and helps you more easily master complex concepts. A companion Evolve website offers online access to a wealth of additional review questions, content updates, and web links.

PART 1: BASIC IMMUNOLOGIC MECHANISMS 1. An Overview of Immunology 2. Antigens and Antibodies 3. The Cells and Cellular Activities of the Immune System: Granulocytes and Mononuclear Cells 4. The Cells and Cellular Activities of the Immune System: Lymphocytes and Plasma Cells 5. Soluble Mediators of the Immune System

PART 2: THE THEORY OF IMMUNOLOGIC AND SEROLOGIC PROCEDURES 6. Safety and Basic Techniques in the Immunology-Serology Laboratory 7. Quality Assurance and Quality Control NEW! 8. Basic Serologic Laboratory Techniques NEW! 9. Point-of-Care Testing NEW! 10. Agglutination Methods 11. Electrophoresis Techniques 12. Labeling Techniques in Immunoassay 13. Automated Procedures 14. Molecular Techniques

PART 3: IMMUNOLOGIC MANIFESTATIONS OF INFECTIOUS DISEASES 15. The Immune Response in Infectious Diseases 16. A Primer on Vaccines NEW! 17. Streptococcal Infections 18. Syphilis 19. Tick-Borne Diseases 20. Toxoplasmosis 21. Cytomegalovirus 22. Infectious Mononucleosis 23. Viral Hepatitis 24. Rubella Infection 25. Acquired Immunodeficiency Syndrome (AIDS)

PART 4: IMMUNOLOGICALLY AND SEROLOGICALLY RELATED DISORDERS 26. Hypersensitivity Reactions 27. Immunoproliferative Disorders 28. Autoimmune Disorders 29. Systemic Lupus Erythematosus 30. Rheumatoid Arthritis 31. Solid Organ Transplantation 32. Bone Marrow Transplantation 33. Tumor Immunology Appendixes A. Answers to Review Questions B. Diagnostic Tests in Medical Laboratory Immunology Glossary