With a balance of topic coverage and depth this updated third edition covers the subject of biochemistry, and
reflects the advances made in this field since the second edition published in 1981. These advances are incorporated
without loss of historical perspective and without obscuring the main goal of the text: to teach the enduring fundamentals
of the discipline. Included in the third edition is a completely reorganized part one introducing the flow of information
from gene to protein. It emphasizes the growing interrelatedness of molecular biology and biochemistry, and acquaints
one with experimental methods of both disciplines. Also included is 150 new problems and a wealth of new material
on molecular genetics and cellular processes.
Table of Contents
PART I THE MOLECULAR DESIGN OF LIFE
1. Biochemistry: An Evolving Science
2. Protein Composition and Structure
3. Exploring Proteins and Proteomes
4. DNA, RNA, and the Flow of Genetic Information
5. Exploring Genes and Genomes
6. Exploring Evolution and Bioinformatics
7. Hemoglobin: Portrait of a Protein in Action
8. Enzymes: Basic Concepts and Kinetics
9. Catalytic Strategies
10. Regulatory Strategies
11. Carbohydrates
12. Lipids and Cell Membranes
13. Membrane Channels and Pumps
14. Signal-Transduction Pathways
PART II TRANSDUCING AND STORING ENERGY
15. Metabolism: Basic Concepts and Design
16. Glycolysis and Gluconeogenesis
17. The Citric Acid Cycle
18. Oxidative Phosphorylation
19. The Light Reactions of Photosynthesis
20. The Calvin Cycle and the Pentose Phosphate Pathway
21. Glycogen Metabolism
22. Fatty Acid Metabolism
23 . Protein Turnover and Amino Acid Catabolism
PART III SYNTHESIZING THE MOLECULES OF LIFE
24. The Biosynthesis of Amino Acids
25. Nucleotide Biosynthesis
26. The Biosynthesis of Membrane Lipids and Steroids
27. The Integration of Metabolism
28. DNA Replication, Repair, and Recombination
29. RNA Synthesis and Processing
30. Protein Synthesis
31. The Control of Gene Expression
PART IV RESPONDING TO ENVIRONMENTAL CHANGES
32. Sensory Systems
33. The Immune System
34. Molecular Motors
35. Drug Development
